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Two side effects of opioids — growing tolerance to the drugs and increased sensitivity to pain — may be specifically caused by the drugs’ effect on peripheral pain neurons in the body, not those in the spinal cord or brain, according to a new study.
AAU Universities Battle the Opioid Crisis | Treatment & Prevention | University Research | Stanford UniversityBy combining computer simulations with laboratory experiments, an international research team revealed something new about a molecular pathway that enables roughly half of all medications to achieve their desired effects – but is also responsible for many side effects.
University Research | AAU Universities Battle the Opioid Crisis | Treatment & Prevention | Stanford UniversityResearchers have identified a novel compound that appears to exhibit painkilling power comparable to morphine but lacks that drug’s most lethal property: respiratory suppression, which results in some 30,000 drug overdose deaths annually in the United States.
University Research | AAU Universities Battle the Opioid Crisis | Treatment & Prevention | Stanford UniversityHospital discharges related to prescription opioids have declined slightly in recent years, but heroin-related discharges have surged, according to a new study led by researchers at the Stanford University School of Medicine.
AAU Universities Battle the Opioid Crisis | University Research | The Crisis | Stanford UniversityMost prescriptions for opioid painkillers are made by the broad swath of U.S. general practitioners, not by a limited group of specialists, according to a study by researchers at the Stanford University School of Medicine.
AAU Universities Battle the Opioid Crisis | University Research | The Crisis | Stanford UniversityThe prevailing practice for treating addiction to painkillers led from the physician’s office to the worst man-made epidemic in modern medical history.
University Research | AAU Universities Battle the Opioid Crisis | The Crisis | University of WashingtonPenn State Health is leading the creation of a new system to ensure people in south-central Pennsylvania with opioid use disorder receive the treatment they need.
University Research | AAU Universities Battle the Opioid Crisis | Serving Local Communities | The Pennsylvania State UniversityThe majority of patients misusing both opioids and benzodiazepines (BZDs) recognize the risks of overdose and substance dependence, but need more education and motivation to stop concurrent use, says new research led by a School of Public Health addiction expert.
University Research | AAU Universities Battle the Opioid Crisis | Treatment & Prevention | Boston UniversityEconomic conditions account for less than 10 percent of drug-related fatalities, which have increased by more than 210 percent from 1999 to 2015, according to new research.
University Research | AAU Universities Battle the Opioid Crisis | The Crisis | University of VirginiaResearchers are developing drug delivery patches that would be worn on the skin, like a bandage, to deliver non-addictive pain medicine for chronic lower-back pain and post-surgery pain.
University Research | AAU Universities Battle the Opioid Crisis | Treatment & Prevention | University of Virginia