The University of Maryland, College Park has established several initiatives to improve undergraduate education in STEM disciplines and to implement robust, evidence-based reforms. These include new introductory courses in biology and physics that focus on mastery of complex physical, chemical, mathematical, and biological concepts; incorporation of undergraduate learning assistants; creation of hybrid lecture/computer-based active learning versions of mathematics courses; targeted redesign of STEM courses with traditionally high numbers of failures and withdrawals; and a campus-wide, proposal-driven process for course transformation. Campus-wide initiatives include a UTeach replication for STEM teacher preparation (called Terrapin Teachers), creation of a Teaching and Learning Transformation Center to better engage faculty and to create a hub for analysis and evaluation of reform efforts, and establishment of a new First-Year Innovation & Research Experience.