AAU submits comments to provide input in response to the “Dear Colleague” Letter issued by NSF on May 4, 2023 regarding the development of the U.S. Research Security and Integrity Information Sharing Analysis Organization. The letter outlines AAU's support and necessary collaboration with university officials for a risk-assessment center that will help support the research community’s efforts to address risks while continuing to encourage and support the international scientific research collaboration necessary for scientific advancement and innovation.